IRF5 anticorps (Middle Region)

N° du produit ABIN2779405

Cité dans 1 publication. Cet anticorps anti-IRF5 Polyclonal Lapin (ABIN2779405) détecte spécifiquement IRF5 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Cheval, Chien, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour IRF5 anticorps (Middle Region) (ABIN2779405)

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Cheval, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRF5 anticorps

Épitope: Middle Region

Séquence: IFFCFGEEWP DRKPREKKLI TVQVVPVAAR LLLEMFSGEL SWSADSIRLQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human IRF5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 498 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IRF5 (ABIN2779405)

Coletta, Cullington, Clark, Cleland: "Clinical trials update from European Society of Cardiology meeting 2008: TIME-CHF, BACH, BEAUTIFUL, GISSI-HF, and HOME-HF." dans: European journal of heart failure, Vol. 10, Issue 12, pp. 1264-7, (2008) (PubMed).

Détails sur IRF5

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Autre désignation: IRF5

Sujet: IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.
Alias Symbols: SLEB10
Protein Interaction Partner: SGTA, IRF5, COPS7B, COPS4, COPS5, COPS6, COPS8, COPS2, COPS3, UBC, GPS1, TRAF6, MYD88, RGS3, PPM1G, IRF6, HIVEP1, GRB2, CHUK, ALPI, MAVS, GTPBP2, CEP152, GTPBP1, SIN3A, NCOR2, NCOR1, KAT2B, HDAC1, EP300, CREBBP, TRIM15, IKBKE, TBK1, IRF3, XPO1,
Protein Size: 498

Poids moléculaire: 56 kDa

ID gène: 3663

NCBI Accession: NM_032643, NP_116032

UniProt: Q13568

Pathways: Signalisation TLR, Autophagy