MYCN anticorps (C-Term)

N° du produit ABIN2779428

Cet anticorps anti-MYCN est un anticorps Lapin Polyclonal détectant MYCN dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc et Lapin.

Aperçu rapide pour MYCN anticorps (C-Term) (ABIN2779428)

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYCN est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MYCN anticorps

Épitope: C-Term

Séquence: EDAPPQKKIK SEASPRPLKS VIPPKAKSLS PRNSDSEDSE RRRNHNILER

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 77%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MYCN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 464 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MYCN

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Autre désignation: MYCN

Sujet: MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas
Alias Symbols: NMYC, ODED, MODED, N-myc, bHLHe37
Protein Interaction Partner: TRIM32, UBC, HDAC5, NMI, MAX, CDKN2A, GRK5, ZBTB17, SIRT1, YEATS4, CSNK1E, FBXW7, PIAS2, AURKA, SP1, NTRK1, NGFR, HDAC2, CSNK2A1, YAF2, MXD1, CSNK2A2, SLC1A2,
Protein Size: 464

Poids moléculaire: 50 kDa

ID gène: 4613

NCBI Accession: NM_005378, NP_005369

UniProt: P04198