PAWR anticorps (Middle Region)

N° du produit ABIN2779443

Cet anticorps Lapin Polyclonal détecte spécifiquement PAWR dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Cheval, Lapin et Cobaye.

Aperçu rapide pour PAWR anticorps (Middle Region) (ABIN2779443)

Antigène: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Reactivité: Humain, Souris, Rat, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAWR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PAWR anticorps

Épitope: Middle Region

Séquence: VNIPAAECLD EYEDDEAGQK ERKREDAITQ QNTIQNEAVN LLDPGSSYLL

Homologie: Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PAWR. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PAWR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 340 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAWR

Antigène: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Autre désignation: PAWR

Sujet: The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
Alias Symbols: PAR4, Par-4
Protein Interaction Partner: FBXO45, UBC, EED, FAM129B, SNX6, CAND1, VPS29, JMJD6, STAT1, SNX2, SHMT2, SHMT1, PPM1G, IDE, H3F3A, CARS, ATP6V1C1, APEH, PAN2, DRD2, DAPK3, SQSTM1, PRKCZ, Spsb4, Spsb2, SPSB1, FBXO25, HSPA5, Cep350, Kif23, THAP1, SLC5A7, AATF, TFPT, PAWR, WT1, RRAS2, ATP
Protein Size: 340

Poids moléculaire: 37 kDa

ID gène: 5074

NCBI Accession: NM_002583, NP_002574

UniProt: O75796