PAX4 anticorps (Middle Region)

N° du produit ABIN2779444

Détail du produit anti-PAX4 anticorps

Antigène: PAX4 (Paired Box 4 (PAX4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX4 est non-conjugé

Application: Western Blotting (WB)

Séquence: RTIFSPSQAE ALEKEFQRGQ YPDSVARGKL ATATSLPEDT VRVWFSNRRA

Specificité: 100 % homologous to all 3 isoforms (38, 30, 37 kDa).

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against PAX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PAX4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 343 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PAX4 (ABIN2779444)

Zhang, Smyrk, Oliveira, Lohse, Zhang, Johnson, Lloyd: "KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers." dans: The American journal of surgical pathology, Vol. 33, Issue 10, pp. 1562-9, (2010) (PubMed).

Détails sur PAX4

Antigène: PAX4 (Paired Box 4 (PAX4))

Autre désignation: PAX4 (PAX4 Produits)

Synonymes: anticorps KPD, anticorps MODY9, anticorps Pax-4, anticorps PAX4, anticorps paired box 4, anticorps PAX4, anticorps Pax4

Sujet: PAX4 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing .- cells.
Alias Symbols: KPD, MGC129960, MODY9
Protein Interaction Partner: GMCL1,
Protein Size: 343

Poids moléculaire: 37 kDa

ID gène: 5078

NCBI Accession: NM_006193, NP_006184

UniProt: O43316