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PAX4 anticorps (Internal Region)

PAX4 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259146
  • Antigène Voir toutes PAX4 Anticorps
    PAX4 (Paired Box 4 (PAX4))
    Épitope
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 29
    • 14
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 23
    • 5
    • 1
    Lapin
    Clonalité
    • 25
    • 4
    Polyclonal
    Conjugué
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PAX4 est non-conjugé
    Application
    • 22
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    PAX4 Antibody detects endogenous levels of total PAX4.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human PAX4, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PAX4 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    PAX4 (Paired Box 4 (PAX4))
    Autre désignation
    PAX4 (PAX4 Produits)
    Synonymes
    anticorps KPD, anticorps MODY9, anticorps Pax-4, anticorps PAX4, anticorps paired box 4, anticorps PAX4, anticorps Pax4
    Sujet

    Description: Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.

    Gene: PAX4

    Poids moléculaire
    42 kDa
    ID gène
    5078
    UniProt
    O43316
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