DVL1 anticorps (Middle Region)

N° du produit ABIN2779456

Détail du produit anti-DVL1 anticorps

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DVL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LKITIANAVI GADVVDWLYT HVEGFKERRE ARKYASSLLK HGFLRHTVNK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 87%

Attributs du produit: This is a rabbit polyclonal antibody against DVL1. It was validated on Western Blot.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DVL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 353 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DVL1

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Autre désignation: DVL1 (DVL1 Produits)

Sujet: DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Alias Symbols: DVL, MGC54245, DVL1L1
Protein Interaction Partner: NCK2, TRIM69, NUMA1, HUWE1, UBC, DVL2, WWOX, SIPA1, PSMA3, LRRK2, ITCH, HECW1, NEDD4, ANXA7, SDC4, NKD2, CYLD, SIRT1, CCDC88C, VANGL1, CXXC4, PPM1A, DYNLT1, HDHD2, BRD7, DAAM1, AXIN1, USP13, SMAD3, SMAD7, FRAT1, RAC1, DVL3, SMAD2, DVL1, SMAD4, CSNK1D, CSN
Protein Size: 353

Poids moléculaire: 38 kDa

ID gène: 1855

NCBI Accession: NM_004421

UniProt: A6NKG8

Pathways: Signalisation WNT, Synaptic Membrane, Skeletal Muscle Fiber Development