TLE2 anticorps (N-Term)

N° du produit ABIN2779582

L’anticorps anti-TLE2 Polyclonal Lapin est utilisé pour la détection de TLE2 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye et Porc. Il a été validé pour WB.

Aperçu rapide pour TLE2 anticorps (N-Term) (ABIN2779582)

Antigène: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TLE2 anticorps

Épitope: N-Term

Fonction: TLE2 Antibody - N-terminal region

Séquence: VEEERPSGPG GGGKQRADEK EPSGPYESDE DKSDYNLVVD EDQPSEPPSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TLE2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114226

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TLE2

Antigène: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Autre désignation: TLE2

Sujet:

Background Information: TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.

Gene Name: Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)

Alternative Symbols: ESG, ESG2, GRG2

Protein Name: Transducin-like enhancer protein 2

Poids moléculaire: 80kDa

ID gène: 7089

NCBI Accession: NP_003251

UniProt: Q04725

Pathways: Signalisation WNT