HDAC1 anticorps (Middle Region)

N° du produit ABIN2779587

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye, Cheval et Saccharomyces cerevisiae.

Aperçu rapide pour HDAC1 anticorps (Middle Region) (ABIN2779587)

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HDAC1 anticorps

Épitope: Middle Region

Fonction: HDAC1 Antibody - middle region

Séquence: EKIKQRLFEN LRMLPHAPGV QMQAIPEDAI PEESGDEDED DPDKRISICS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against HDAC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HDAC1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32358-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HDAC1

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Autre désignation: HDAC1

Sujet:

Background Information: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Histone deacetylase 1

Alternative Symbols: HD1, RPD3, KDAC1, GON-10, RPD3L1

Protein Name: Histone deacetylase 1

Poids moléculaire: 55kDa

ID gène: 3065

NCBI Accession: NP_004955

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis