TLE4 anticorps (N-Term)

N° du produit ABIN2779602

Cet anticorps anti-TLE4 est un anticorps Lapin Polyclonal détectant TLE4 dans WB et IHC. Adapté pour Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour TLE4 anticorps (N-Term) (ABIN2779602)

Antigène: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TLE4 anticorps

Épitope: N-Term

Séquence: GAEKHRNSAD YSSESKKQKT EEKEIAARYD SDGEKSDDNL VVDVSNEDPS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TLE4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 773 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TLE4

Antigène: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Autre désignation: TLE4

Sujet: TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: BCE-1, E(spI), ESG, ESG4, GRG4, BCE1
Protein Interaction Partner: SRPK2, POU2F2, UBC, LIG4, BRCA1, WDR77, PRMT5, PPM1B, CUX1, OTX1, OTX2, TLE4, PAX5, POU2F1, MSX1, HDAC1,
Protein Size: 773

Poids moléculaire: 84 kDa

ID gène: 7091

NCBI Accession: NM_007005, NP_008936

UniProt: Q04727

Pathways: Signalisation WNT