TLE4 anticorps (N-Term)
Aperçu rapide pour TLE4 anticorps (N-Term) (ABIN2779602)
Antigène
Voir toutes TLE4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- TLE4 Antibody - N-terminal region
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Séquence
- GAEKHRNSAD YSSESKKQKT EEKEIAARYD SDGEKSDDNL VVDVSNEDPS
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against TLE4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32381-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TLE4 (Transducin-like Enhancer Protein 4 (TLE4))
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Autre désignation
- TLE4
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Sujet
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Background Information: TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Gene Name: Transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
Alternative Symbols: ESG, BCE1, ESG4, GRG4, BCE-1, Grg-4, E(spI), E(spl)
Protein Name: Transducin-like enhancer protein 4
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Poids moléculaire
- 84kDa
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ID gène
- 7091
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NCBI Accession
- NP_008936
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UniProt
- Q04727
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Pathways
- Signalisation WNT
Antigène
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