SIRT3 anticorps (Middle Region)
Aperçu rapide pour SIRT3 anticorps (Middle Region) (ABIN2779609)
Antigène
Voir toutes SIRT3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- SIRT3 Antibody - middle region
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Séquence
- SGIPDFRSPG SGLYSNLQQY DLPYPEAIFE LPFFFHNPKP FFTLAKELYP
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Homologie
- Dog: 100%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 77%, Zebrafish: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against SIRT3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SIRT3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32388-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SIRT3 (Sirtuin 3 (SIRT3))
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Autre désignation
- SIRT3
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Sujet
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Background Information: SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.
Gene Name: Sirtuin 3
Alternative Symbols: SIR2L3
Protein Name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
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Poids moléculaire
- 44kDa
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ID gène
- 23410
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NCBI Accession
- NP_036371
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UniProt
- Q9NTG7
Antigène
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