ZEB1 anticorps (N-Term)

N° du produit ABIN2779631

L’anticorps Lapin Polyclonal anti-ZEB1 a été validé pour WB et IF. Il convient pour détecter ZEB1 dans des échantillons de Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache) et Cobaye. Il y a 1 publication disponible.

Aperçu rapide pour ZEB1 anticorps (N-Term) (ABIN2779631)

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZEB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-ZEB1 anticorps

Épitope: N-Term

Séquence: KDDECESDAE NEQNHDPNVE EFLQQQDTAV IFPEAPEEDQ RQGTPEASGH

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ZEB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ZEB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1124 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ZEB1 (ABIN2779631)

Lobert, Graichen, Morris: "Coordinated regulation of ?-tubulin isotypes and epithelial-to-mesenchymal transition protein ZEB1 in breast cancer cells." dans: Biochemistry, Vol. 52, Issue 32, pp. 5482-90, (2013) (PubMed).

Détails sur ZEB1

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Autre désignation: ZEB1

Sujet: ZEB1 is a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM].
Alias Symbols: AREB6, BZP, MGC133261, NIL-2-A, NIL-2A, TCF8, ZEB, ZFHEP, ZFHX1A, FECD6, NIL2A, PPCD3, DELTAEF1
Protein Interaction Partner: SUMO1, CDK6, GTF2A1, UBR4, SUMO2, SIRT1, SOX2, CTBP2, CTBP1, SMAD7, SMAD6, SMARCA4, SERPINH1, SMAD3, EP300, DRAP1, KAT5, SMAD2, SMAD1, CDH1,
Protein Size: 1124

Poids moléculaire: 124 kDa

ID gène: 6935

NCBI Accession: NM_030751, NP_110378

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation