PTF1A anticorps (N-Term)

N° du produit ABIN2779701

Détail du produit anti-PTF1A anticorps

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTF1A est non-conjugé

Application: Western Blotting (WB)

Séquence: PLEDGDELLA DEQAEVEFLS HQLHEYCYRD GACLLLQPAP PAAPLALAPP

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 93%, Yeast: 75%

Attributs du produit: This is a rabbit polyclonal antibody against PTF1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PTF1A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 328 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTF1A

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Autre désignation: PTF1A (PTF1A Produits)

Sujet: PTF1A is a pancreas specific transcription factor. Mammalian studies have implicated important roles for the basic helix-loop-helix transcription factor PTF1A-p48 in the development of both exocrine and endocrine pancreas. This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PTF1-p48, bHLHa29
Protein Interaction Partner: TCF12,
Protein Size: 328

Poids moléculaire: 35 kDa

ID gène: 256297

NCBI Accession: NM_178161, NP_835455

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway