WWTR1 anticorps (N-Term)

N° du produit ABIN2779708

L’anticorps anti-WWTR1 Polyclonal Lapin est utilisé pour la détection de WWTR1 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye et Lapin. Il a été validé pour WB.

Aperçu rapide pour WWTR1 anticorps (N-Term) (ABIN2779708)

Antigène: WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWTR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WWTR1 anticorps

Épitope: N-Term

Fonction: WWTR1 Antibody - N-terminal region

Séquence: PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against WWTR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human WWTR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115959

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur WWTR1

Antigène: WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

Autre désignation: WWTR1

Sujet:

Background Information: TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.

Gene Name: WW domain containing transcription regulator 1

Alternative Symbols: TAZ

Protein Name: WW domain-containing transcription regulator protein 1

Poids moléculaire: 44 kDa

ID gène: 25937

NCBI Accession: NP_056287

UniProt: Q9GZV5

Pathways: Regulation of Lipid Metabolism by PPARalpha