HIPK2 anticorps (Middle Region)
Aperçu rapide pour HIPK2 anticorps (Middle Region) (ABIN2779735)
Antigène
Voir toutes HIPK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- HIPK2 Antibody - middle region
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Séquence
- MWSLGCVIAE LFLGWPLYPG ASEYDQIRYI SQTQGLPAEY LLSAGTKTTR
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Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%
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Attributs du produit
- This is a rabbit polyclonal antibody against HIPK2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human HIPK2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32586-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Heat shock modulates the subcellular localization, stability, and activity of HIPK2." dans: Biochemical and biophysical research communications, Vol. 472, Issue 4, pp. 580-4, (2016) (PubMed).
: "v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300." dans: Oncogene, Vol. 28, Issue 26, pp. 2446-55, (2009) (PubMed).
: "Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1." dans: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4682-9, (2008) (PubMed).
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- HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
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Autre désignation
- HIPK2
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Sujet
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Background Information: HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
Gene Name: Homeodomain interacting protein kinase 2
Alternative Symbols: PRO0593
Protein Name: Homeodomain-interacting protein kinase 2
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Poids moléculaire
- 120kDa
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ID gène
- 28996
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NCBI Accession
- NP_073577
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UniProt
- Q9H2X6
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Pathways
- Cycle Cellulaire
Antigène
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