KAP1 anticorps (N-Term)

N° du produit ABIN2779797

Cet anticorps anti-KAP1 Polyclonal Lapin (ABIN2779797) détecte spécifiquement KAP1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cheval, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour KAP1 anticorps (N-Term) (ABIN2779797)

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-KAP1 anticorps

Épitope: N-Term

Séquence: PLVLFCESCD TLTCRDCQLN AHKDHQYQFL EDAVRNQRKL LASLVKRLGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TRIM28. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM28

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 835 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KAP1

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Autre désignation: TRIM28

Sujet: TRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING,a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ29029, KAP1, RNF96, TF1B, TIF1B
Protein Interaction Partner: WWOX, ERLIN2, HUWE1, SUMO1, UBC, SPRTN, SENP7, HAUS2, MAGEC2, CBX5, WHSC1, UBE2I, AURKA, SUMO2, SUMO3, RNF4, CEP250, TRIM28, HIF1A, CHD3, ATM, ZNF350, STAU1, HIST3H3, LYN, NEDD8, MDM2, ZBTB1, RPA3, RPA2, RPA1, RNF2, SUZ12, EZH2, BMI1, EED, BRCC3, WRNIP1,
Protein Size: 835

Poids moléculaire: 88 kDa

ID gène: 10155

NCBI Accession: NM_005762, NP_005753

UniProt: Q13263

Pathways: Signalisation Hedgehog, Positive Regulation of Response to DNA Damage Stimulus