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SMAD6 anticorps (N-Term)

SMAD6 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cobaye, Cheval, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779804
  • Antigène Voir toutes SMAD6 Anticorps
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    Épitope
    • 15
    • 9
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 51
    • 27
    • 11
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cobaye, Cheval, Poisson zèbre (Danio rerio)
    Hôte
    • 53
    • 14
    Lapin
    Clonalité
    • 55
    • 12
    Polyclonal
    Conjugué
    • 40
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMAD6 est non-conjugé
    Application
    • 58
    • 39
    • 15
    • 11
    • 6
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    APRDASDPLA GAALEPAGGG RSREARSRLL LLEQELKTVT YSLLKR
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against SMAD6. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD6
    Top Product
    Discover our top product SMAD6 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 496 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    Autre désignation
    SMAD6 (SMAD6 Produits)
    Synonymes
    anticorps madh6, anticorps madh7, anticorps Xsmad6, anticorps hst17432, anticorps AOVD2, anticorps HsT17432, anticorps MADH6, anticorps MADH7, anticorps Madh6, anticorps b2b390Clo, anticorps Smad6-like, anticorps smad6, anticorps wu:fb22g05, anticorps SMAD family member 6, anticorps SMAD family member 6a, anticorps smad6, anticorps SMAD6, anticorps Smad6, anticorps smad6a
    Sujet
    SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
    Alias Symbols: MADH6, MADH7, HsT17432
    Protein Interaction Partner: ITCH, SMURF2, BPIFA1, NEDD4L, WWP2, WWP1, USP15, USP11, PIGR, NASP, LYZ, KPNA2, CTBP2, CTBP1, UBC, ACVR1, UBE2O, BAMBI, STAMBP, ACTR1B, TGFBR1, MYD88, SMAD1, BMPR2, BMPR1B, BMPR1A, ACVR2B, ACVR1B, SMURF1, PELI1, CUL2, ELAVL1, SMAD5, RPS6KA5, TSC22D1, MAPK
    Protein Size: 496
    Poids moléculaire
    53 kDa
    ID gène
    4091
    NCBI Accession
    NM_005585, NP_005576
    UniProt
    O43541
    Pathways
    Chromatin Binding
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