SMAD6 anticorps (N-Term)

N° du produit ABIN2779804

L’anticorps anti-SMAD6 Polyclonal Lapin est utilisé pour la détection de SMAD6 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC.

Aperçu rapide pour SMAD6 anticorps (N-Term) (ABIN2779804)

Antigène: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SMAD6 anticorps

Épitope: N-Term

Fonction: SMAD6 Antibody - N-terminal region

Séquence: APRDASDPLA GAALEPAGGG RSREARSRLL LLEQELKTVT YSLLKR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SMAD6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111902

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMAD6

Antigène: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Autre désignation: SMAD6

Sujet:

Background Information: SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.

Gene Name: SMAD family member 6

Alternative Symbols: AOVD2, MADH6, MADH7, HsT17432

Protein Name: Mothers against decapentaplegic homolog 6

Poids moléculaire: 53kDa

ID gène: 4091

NCBI Accession: NP_005576

UniProt: O43541

Pathways: Chromatin Binding