NK2 Homeobox 5 anticorps (N-Term)
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- Antigène Voir toutes NK2 Homeobox 5 (NKX2-5) Anticorps
- NK2 Homeobox 5 (NKX2-5)
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NK2 Homeobox 5 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MFPSPALTPT PFSVKDILNL EQQQRSLASG DLSARLEATL APASCMLAAF
- Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 80%, Mouse: 100%, Rabbit: 86%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against Nkx2-5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the n terminal region of mouse Nkx2-5
- Top Product
- Discover our top product NKX2-5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 318 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NK2 Homeobox 5 (NKX2-5)
- Autre désignation
- Nkx2-5 (NKX2-5 Produits)
- Synonymes
- anticorps CHNG5, anticorps CSX, anticorps CSX1, anticorps HLHS2, anticorps NKX2.5, anticorps NKX2E, anticorps NKX4-1, anticorps VSD3, anticorps Csx, anticorps Nkx-2.5, anticorps Nkx2.5, anticorps tinman, anticorps nk2.5, anticorps nkx2-5, anticorps zgc:111912, anticorps AR2, anticorps XNkx2-5, anticorps csx, anticorps nkx-2.5, anticorps nkx2-5b, anticorps nkx2.5, anticorps NKX2-5, anticorps Nkx2-5, anticorps csx1, anticorps nkx2e, anticorps XNkx-2.5, anticorps CNKX-2.5, anticorps NKX-2.5, anticorps NK2 homeobox 5, anticorps NK2 homeobox 5 S homeolog, anticorps NKX2-5, anticorps Nkx2-5, anticorps nkx2.5, anticorps nkx2-5.S, anticorps nkx2-5
- Sujet
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Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.
Alias Symbols: Csx, Nkx-2.5, Nkx2.5, tinman
Protein Interaction Partner: Tbx5, Foxh1, Hand2, Hand1, Mef2c, Tbx1, Prox1, Smarca4, SRF,
Protein Size: 318 - Poids moléculaire
- 34 kDa
- ID gène
- 18091
- NCBI Accession
- NM_008700, NP_032726
- UniProt
- P42582
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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