IRF5 anticorps (N-Term)

N° du produit ABIN2779987

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF5 dans WB. Il présente une réactivité envers Souris et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour IRF5 anticorps (N-Term) (ABIN2779987)

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRF5 anticorps

Épitope: N-Term

Séquence: CSNGPAPTES QPTDDYVLGE EEEEEEEELQ RMLPGLSITE PALPGPPNAP

Homologie: Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 497 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IRF5 (ABIN2779987)

Takaoka, Yanai, Kondo, Duncan, Negishi, Mizutani, Kano, Honda, Ohba, Mak, Taniguchi: "Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." dans: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).

Détails sur IRF5

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Autre désignation: IRF5

Sujet: The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
Alias Symbols: mirf5, AW491843
Protein Interaction Partner: Ubc, Traf6, Irak1, Zfp764, Myd88, Il12b,
Protein Size: 497

Poids moléculaire: 55 kDa

ID gène: 27056

NCBI Accession: NM_012057, NP_036187

UniProt: P56477

Pathways: Signalisation TLR, Autophagy