IRF5 anticorps (N-Term)
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- Antigène Voir toutes IRF5 Anticorps
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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Épitope
- N-Term
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF5 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- CSNGPAPTES QPTDDYVLGE EEEEEEEELQ RMLPGLSITE PALPGPPNAP
- Homologie
- Mouse: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5
- Top Product
- Discover our top product IRF5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 497 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." dans: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).
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Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." dans: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).
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- Antigène
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
- Autre désignation
- IRF5 (IRF5 Produits)
- Synonymes
- anticorps IRF5, anticorps irf5, anticorps SLEB10, anticorps AW491843, anticorps mirf5, anticorps im:7155364, anticorps zgc:76986, anticorps interferon regulatory factor 5, anticorps interferon regulatory factor 5 L homeolog, anticorps IRF5, anticorps irf5, anticorps Irf5, anticorps irf5.L
- Sujet
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The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
Alias Symbols: mirf5, AW491843
Protein Interaction Partner: Ubc, Traf6, Irak1, Zfp764, Myd88, Il12b,
Protein Size: 497 - Poids moléculaire
- 55 kDa
- ID gène
- 27056
- NCBI Accession
- NM_012057, NP_036187
- UniProt
- P56477
- Pathways
- Signalisation TLR, Autophagy
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