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IRF5 anticorps (N-Term)

IRF5 Reactivité: Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779987
  • Antigène Voir toutes IRF5 Anticorps
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Épitope
    • 9
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 72
    • 47
    • 21
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    Souris, Rat
    Hôte
    • 72
    • 10
    • 1
    • 1
    Lapin
    Clonalité
    • 64
    • 20
    Polyclonal
    Conjugué
    • 52
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp IRF5 est non-conjugé
    Application
    • 47
    • 30
    • 12
    • 11
    • 10
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    CSNGPAPTES QPTDDYVLGE EEEEEEEELQ RMLPGLSITE PALPGPPNAP
    Homologie
    Mouse: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5
    Top Product
    Discover our top product IRF5 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 497 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Takaoka, Yanai, Kondo, Duncan, Negishi, Mizutani, Kano, Honda, Ohba, Mak, Taniguchi: "Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." dans: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).

  • Antigène
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Autre désignation
    IRF5 (IRF5 Produits)
    Synonymes
    anticorps IRF5, anticorps irf5, anticorps SLEB10, anticorps AW491843, anticorps mirf5, anticorps im:7155364, anticorps zgc:76986, anticorps interferon regulatory factor 5, anticorps interferon regulatory factor 5 L homeolog, anticorps IRF5, anticorps irf5, anticorps Irf5, anticorps irf5.L
    Sujet
    The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
    Alias Symbols: mirf5, AW491843
    Protein Interaction Partner: Ubc, Traf6, Irak1, Zfp764, Myd88, Il12b,
    Protein Size: 497
    Poids moléculaire
    55 kDa
    ID gène
    27056
    NCBI Accession
    NM_012057, NP_036187
    UniProt
    P56477
    Pathways
    Signalisation TLR, Autophagy
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