Estrogen Receptor alpha anticorps (N-Term)
Aperçu rapide pour Estrogen Receptor alpha anticorps (N-Term) (ABIN2780328)
Antigène
Voir toutes Estrogen Receptor alpha (ESR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LERPLGEVYL DSSKPAVYNY PEGAAYEFNA AAAANAQVYG QTGLPYGPGS
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Homologie
- Cow: 93%, Dog: 79%, Goat: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against ESR1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ESR1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 595 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Autre désignation
- ESR1
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Sujet
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ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodi
Alias Symbols: DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
Protein Interaction Partner: SRC, DDX5, POLR2C, POLR2B, POLR2A, MSH2, TTC5, KAT5, NCOA2, BRCA1, MED24, UBC, PSMB9, MED1, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, ASCC1, TRRAP, PHB2, NCOR1, NCOA1, PIK3CA, IGF1R, HDAC1, NSD1, WIPI1, ESR1, ZNF131, RANBP9,
Protein Size: 595 -
Poids moléculaire
- 66 kDa
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ID gène
- 2099
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NCBI Accession
- NM_000125, NP_000116
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UniProt
- P03372
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Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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