MEFV anticorps (N-Term)
Aperçu rapide pour MEFV anticorps (N-Term) (ABIN2780331)
Antigène
Voir toutes MEFV AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MAKTPSDHLL STLEELVPYD FEKFKFKLQN TSVQKEHSRI PRSQIQRARP
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Homologie
- Horse: 85%, Human: 100%, Pig: 77%, Rabbit: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against MEFV. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 781 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MEFV (Mediterranean Fever (MEFV))
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Autre désignation
- MEFV
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Sujet
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MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors. This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FMF, MEF, MGC126560, MGC126586, TRIM20
Protein Interaction Partner: COG5, PYCARD, PSTPIP1,
Protein Size: 781 -
Poids moléculaire
- 86 kDa
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ID gène
- 4210
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NCBI Accession
- NM_000243, NP_000234
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UniProt
- O15553
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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