MEFV anticorps (N-Term)

N° du produit ABIN2780331

Cet anticorps anti-MEFV Polyclonal Lapin (ABIN2780331) détecte spécifiquement MEFV dans WB. L’anticorps est réactif avec des échantillons de Humain, Cheval, Lapin et Porc.

Aperçu rapide pour MEFV anticorps (N-Term) (ABIN2780331)

Antigène: MEFV (Mediterranean Fever (MEFV))

Reactivité: Humain, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEFV est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MEFV anticorps

Épitope: N-Term

Fonction: MEFV Antibody - N-terminal region

Séquence: MAKTPSDHLL STLEELVPYD FEKFKFKLQN TSVQKEHSRI PRSQIQRARP

Homologie: Horse: 85%, Human: 100%, Pig: 77%, Rabbit: 77%

Attributs du produit: This is a rabbit polyclonal antibody against MEFV. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37973-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MEFV

Antigène: MEFV (Mediterranean Fever (MEFV))

Autre désignation: MEFV

Sujet:

Background Information: MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors. This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Mediterranean fever

Alternative Symbols: FMF, MEF, PAAND, TRIM20

Protein Name: Pyrin

Poids moléculaire: 86kDa

ID gène: 4210

NCBI Accession: NP_000234

UniProt: O15553

Pathways: Positive Regulation of Endopeptidase Activity