TWIST1 anticorps (C-Term)

N° du produit ABIN2780347

Détail du produit anti-TWIST1 anticorps

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cheval, Porc, Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TWIST1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: DKLSKIQTLK LAARYIDFLY QVLQSDELDS KMASCSYVAH ERLSYAFSVW

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TWIST1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TWIST1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 202 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TWIST1 (ABIN2780347)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." dans: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Détails sur TWIST1

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Autre désignation: TWIST1 (TWIST1 Produits)

Synonymes: anticorps scs, anticorps Xtwi, anticorps acs3, anticorps X-twi, anticorps bpes2, anticorps bpes3, anticorps twist, anticorps Xtwist, anticorps MGC69439, anticorps twist1, anticorps ACS3, anticorps BPES2, anticorps BPES3, anticorps CRS1, anticorps SCS, anticorps TWIST, anticorps bHLHa38, anticorps AA960487, anticorps M-Twist, anticorps Pde, anticorps Ska10, anticorps Ska, anticorps Twist, anticorps pdt, anticorps cTwist, anticorps Twist1b, anticorps twist-1, anticorps wu:fd04c01, anticorps zgc:101115, anticorps twist family bHLH transcription factor 1, anticorps twist family bHLH transcription factor 1 S homeolog, anticorps twist basic helix-loop-helix transcription factor 1, anticorps twist homolog 1 (Drosophila), anticorps twist family bHLH transcription factor 1a, anticorps TWIST1, anticorps twist1, anticorps twist1.S, anticorps Twist1, anticorps twist1a

Sujet: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation.TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
Alias Symbols: SCS, ACS3, CRS1, BPES2, BPES3, TWIST, bHLHa38
Protein Interaction Partner: UBC, HOXA5, ETS2, TP53, KAT2B, SETD8, HES6, MTA2, BRAP, TCF3, RELA, PPP2CA, HDAC2, CHD3, TWIST2, ELSPBP1, WDR5, HDAC3, RBBP7, CHD4, SOX2, EP300, TWIST1, GLI3, MYOD1,
Protein Size: 202

Poids moléculaire: 21 kDa

ID gène: 7291

NCBI Accession: NM_000474, NP_000465

UniProt: Q15672

Pathways: Signalisation p53, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity