Progesterone Receptor anticorps (N-Term)

N° du produit ABIN2780349

L’anticorps Lapin Polyclonal anti-Progesterone Receptor a été validé pour WB. Il convient pour détecter Progesterone Receptor dans des échantillons de Humain et Rat.

Aperçu rapide pour Progesterone Receptor anticorps (N-Term) (ABIN2780349)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Progesterone Receptor anticorps

Épitope: N-Term

Séquence: TELKAKGPRA PHVAGGPPSP EVGSPLLCRP AAGPFPGSQT SDTLPEVSAI

Homologie: Human: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PGR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PGR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 933 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: PGR

Sujet: This protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NR3C3, PR
Protein Interaction Partner: BCAS2, SRC, PGR, Dlg4, PARP1, ANP32A, XRCC5, PRKDC, XRCC6, MAGEA11, FKBP5, RBM23, RBM39, KAT2B, BRCA1, STUB1, DNAJC7, PPP5C, FKBP4, BPTF, CDK2, COPS5, NCOA1, UBC, ESR1, NCOA2, CCNA1, NCOA3, STAT3, SP1, Jdp2, Batf3, STAT5B, STAT5A, FGFR2, PRDM2, NCOR2, TAF
Protein Size: 933

Poids moléculaire: 99 kDa

ID gène: 5241

NCBI Accession: NM_000926, NP_000917

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration