PRDM1 anticorps (N-Term)

N° du produit ABIN2780353

Cet anticorps Lapin Polyclonal détecte spécifiquement PRDM1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour PRDM1 anticorps (N-Term) (ABIN2780353)

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRDM1 anticorps

Épitope: N-Term

Séquence: MKMDMEDADM TLWTEAEFEE KCTYIVNDHP WDSGADGGTS VQAEASLPRN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRDM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 789 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRDM1

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Autre désignation: PRDM1

Sujet: PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Alias Symbols: BLIMP1, PRDI-BF1
Protein Interaction Partner: PRMT5, SENP1, EHMT2, PIAS1, SUMO1, IRF2, IRF1, HDAC2, HDAC1, HIST1H1A, MS4A1, HSP90AA1, ATXN1, ELAVL1, KDM1A, IRF4, TLE2, TLE1, AES, PRMT7, HIST2H3A,
Protein Size: 789

Poids moléculaire: 88 kDa

ID gène: 639

NCBI Accession: NM_001198, NP_001189

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation