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SOX4 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement SOX4 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Chévre et Cheval.
N° du produit ABIN2780469
534,11 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour SOX4 anticorps (N-Term) (ABIN2780469)

Antigène

Voir toutes SOX4 Anticorps
SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Reactivité

  • 78
  • 21
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Chévre, Cheval

Hôte

  • 55
  • 25
Lapin

Clonalité

  • 56
  • 24
Polyclonal

Conjugué

  • 38
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SOX4 est non-conjugé

Application

  • 45
  • 25
  • 17
  • 15
  • 13
  • 13
  • 10
  • 10
  • 8
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 17
    • 15
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Fonction

    SOX4 Antibody - N-terminal region

    Séquence

    STASTGGKAD DPSWCKTPSG HIKRPMNAFM VWSQIERRKI MEQSPDMHNA

    Specificité

    Peptide immunogen shares 93 % with human SOX11.

    Homologie

    Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against SOX4. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human SOX4
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112835

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    prevent freeze-thaw cycles

    Stock

    4 °C,-20 °C

    Stockage commentaire

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

    Autre désignation

    SOX4

    Sujet

    Background Information: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: SRY (sex determining region Y)-box 4

    Alternative Symbols: CSS10, EVI16

    Protein Name: Transcription factor SOX-4

    Poids moléculaire

    47 kDa

    ID gène

    6659

    NCBI Accession

    NP_003098

    UniProt

    Q06945
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