TIMELESS anticorps (C-Term)

N° du produit ABIN2780562

Cet anticorps anti-TIMELESS Polyclonal Lapin (ABIN2780562) détecte spécifiquement TIMELESS dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Mouton et Saccharomyces cerevisiae.

Aperçu rapide pour TIMELESS anticorps (C-Term) (ABIN2780562)

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Mouton, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMELESS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TIMELESS anticorps

Épitope: C-Term

Fonction: TIMELESS Antibody - C-terminal region

Séquence: EEEDAVGKEP LKAAPKKRQL LDSDEEQEED EGRNRAPELG APGIQKKKRY

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Mouse: 90%, Rat: 100%, Sheep: 100%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TIMELESS

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38404-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TIMELESS

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Autre désignation: TIMELESS

Sujet:

Background Information: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.

Gene Name: Timeless homolog (Drosophila)

Alternative Symbols: TIM, TIM1, hTIM

Protein Name: Protein timeless homolog

Poids moléculaire: 139kDa

ID gène: 8914

NCBI Accession: NP_003911

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism