TRIM22 anticorps (Middle Region)
Aperçu rapide pour TRIM22 anticorps (Middle Region) (ABIN2780742)
Antigène
Voir toutes TRIM22 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- VDVSGKIAWI LGVHSKISSL NKRKSSGFAF DPSVNYSKVY SRYRPQYGYW
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Homologie
- Human: 100%, Pig: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against TRIM22. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TRIM22
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 498 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRIM22 (Tripartite Motif Containing 22 (TRIM22))
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Autre désignation
- TRIM22
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Sujet
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TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPSTAF50, RNF94, STAF50
Protein Interaction Partner: EIF4E, UBC, TAB2, CASK, CIC, TRIM22, USP7, RERE, ZZZ3, TAF7, CREB1,
Protein Size: 498 -
Poids moléculaire
- 57 kDa
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ID gène
- 10346
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NCBI Accession
- NM_006074, NP_006065
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UniProt
- Q8IYM9
Antigène
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