Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (N-Term) anticorps

Détails pour le produit réf. ABIN2780944, Fournisseur: Connectez-vous pour afficher
Antigène
  • SART3
  • DKFZp469J2418
  • si:ch211-191d15.4
  • wu:fc51h03
  • DSAP1
  • P100
  • RP11-13G14
  • TIP110
  • p110
  • p110(nrb)
  • AU045857
  • mKIAA0156
  • squamous cell carcinoma antigen recognized by T-cells 3
  • squamous cell carcinoma antigen recognized by T-cells 3 L homeolog
  • squamous cell carcinoma antigen recognized by T cells 3
  • SART3
  • sart3
  • sart3.L
  • Sart3
Épitope
N-Term
15
4
3
2
1
1
1
1
1
1
Reactivité
Chien, Cobaye, Cheval, Humain, Porc, Rat (Rattus)
56
13
10
5
4
4
3
3
3
3
2
2
1
1
1
Hôte
Lapin
33
20
3
Clonalité
Polyclonal
Conjugué
Inconjugué
2
2
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
46
30
17
9
8
6
4
1
1
Options
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N° du produit (Fournisseur)
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Immunogène The immunogen is a synthetic peptide directed towards the N terminal region of human SART3
Séquence TSASEPEAES KAGPKADGEE DEVKAARTRR KVLSRAVAAA TYKTMGPAWD
Homologie Dog: 77%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 79%
Attributs du produit This is a rabbit polyclonal antibody against SART3. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Antigène
Autre désignation SART3 (SART3 Antibody Extrait)
Sujet SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.
Alias Symbols: P100, p110, DSAP1, TIP110, p110(nrb), RP11-13G14
Protein Interaction Partner: APBB1, PRPF3, Usp15, AMOT, SF3B1, NUP160, LRPPRC, THRAP3, BCLAF1, VARS, UBC, SUMO2, RAB1A, NEFM, IARS, HIF1A, DSG2, DHX9, MEPCE, HIST2H2BE, HIST2H2AC, RNF2, BMI1, RUFY1, NRBP1, PSME4, AKAP2, COPS5, NUP50, POP7, ARHGEF10, PSMB3, PSMA5, PSMA3, POLR2H, CAST,
Protein Size: 364
Poids moléculaire 40 kDa
ID gène 9733
NCBI Accession NM_014706
Pathways Ribonucleoprotein Complex Subunit Organization
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 364 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images (Fournisseur)
Western Blotting (WB) image for anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (N-Term) antibody (ABIN2780944) WB Suggested Anti-SART3 Antibody Titration: 2.5ug/ml ELISA Titer: 1:62500 Positiv...
Immunohistochemistry (IHC) image for anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (N-Term) antibody (ABIN2780944) Human Liver
Western Blotting (WB) image for anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (N-Term) antibody (ABIN2780944) WB Suggested Anti-SART3 Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.2500 Positive...
Immunohistochemistry (IHC) image for anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) (N-Term) antibody (ABIN2780944) Human Liver
Produit citée dans: Kaji, Mizukoshi, Yamashita, Arai, Sunagozaka, Fushimi, Nakagawa, Yamada, Terashima, Kitahara, Kaneko: "Cellular Immune Responses for Squamous Cell Carcinoma Antigen Recognized by T Cells 3 in Patients with Hepatocellular Carcinoma." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0170291, 2017 (PubMed).

Background publications Liu, Li, Kim, Pace, He: "HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110." dans: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23854-63, 2002 (PubMed).

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