ARNT2 anticorps (N-Term)

N° du produit ABIN2780951

Cet anticorps anti-ARNT2 Polyclonal Lapin (ABIN2780951) détecte spécifiquement ARNT2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Mouton et Lapin.

Aperçu rapide pour ARNT2 anticorps (N-Term) (ABIN2780951)

Antigène: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Mouton, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARNT2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ARNT2 anticorps

Épitope: N-Term

Fonction: ARNT2 Antibody - N-terminal region

Séquence: VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ARNT2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARNT2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39146-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ARNT2

Antigène: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Autre désignation: ARNT2

Sujet:

Background Information: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Gene Name: aryl-hydrocarbon receptor nuclear translocator 2

Alternative Symbols: WEDAS, bHLHe1

Protein Name: ARNT2 protein EMBL AAH51335.1

Poids moléculaire: 23kDa

ID gène: 9915

UniProt: Q86TN1

Pathways: L'effet Warburg