ARNT2 anticorps (N-Term)

N° du produit ABIN2780951

Détail du produit anti-ARNT2 anticorps

Antigène: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Boeuf (Vache), Cobaye, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARNT2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ARNT2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARNT2

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ARNT2

Antigène: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Autre désignation: ARNT2 (ARNT2 Produits)

Synonymes: anticorps bHLHe1, anticorps Hif-2b, anticorps mKIAA0307, anticorps Arnt, anticorps arnt2X, anticorps arnt2a, anticorps chunp6921, anticorps zfARNT2, anticorps zfARNT2a, anticorps zfARNT2b, anticorps zfARNT2c, anticorps arnt2, anticorps MGC53123, anticorps arnt.2, anticorps MGC68805, anticorps ARNT2, anticorps aryl hydrocarbon receptor nuclear translocator 2, anticorps aryl-hydrocarbon receptor nuclear translocator 2, anticorps aryl hydrocarbon receptor nuclear translocator 2 S homeolog, anticorps aryl hydrocarbon receptor nuclear translocator S homeolog, anticorps ARNT2, anticorps Arnt2, anticorps arnt2, anticorps arnt2.S, anticorps arnt.S, anticorps LOC100067423

Sujet: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
Protein Interaction Partner: TRIM42, CEP57L1, RFX6, MIPOL1, DYDC1, SSX2IP, DTX2, SYCE1, RIMBP3, ZNF341, LZTS2, USHBP1, CEP63, CCDC33, NPAS3, RINT1, NDE1, ADAMTSL4, MTUS2, IKZF3, RBCK1, SPAG5, TACC3, CALCOCO2, SORBS3, PDE4DIP, TRAF4, BZRAP1, TFIP11, SSBP3, DGCR6, NCOA3, TRIP6, TRAF2,
Protein Size: 217

Poids moléculaire: 23 kDa

ID gène: 9915

UniProt: Q86TN1

Pathways: L'effet Warburg