ADNP anticorps (N-Term)
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- Antigène Voir toutes ADNP Anticorps
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ADNP est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EDFKQFEPND FYLKNTTWED VGLWDPSLTK NQDYRTKPFC CSACPFSSKF
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against ADNP. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ADNP
- Top Product
- Discover our top product ADNP Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1102 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
- Autre désignation
- ADNP (ADNP Produits)
- Synonymes
- anticorps AA589558, anticorps mKIAA0784, anticorps ADNP1, anticorps activity-dependent neuroprotective protein, anticorps activity dependent neuroprotector homeobox, anticorps activity-dependent neuroprotector homeobox, anticorps Adnp, anticorps ADNP
- Sujet
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Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. ADNP is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. It contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It is also upregulated in normal proliferative tissues. Finally, ADNP may increase the viability of certain cell types through modulation of p53 activity.Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: ADNP1, KIAA0784
Protein Interaction Partner: UBC, SUMO2, EED, RNF2, BMI1, HDAC1, HDAC11, MYC, CDC27, CBX5, PHGDH, RRS1, EBNA1BP2, SAP18, NFIA, SEPT2, EMD, SIRT7, CBX3, CBX1, MAP1LC3B, ARID1A, SMARCC2, SMARCA4,
Protein Size: 1102 - Poids moléculaire
- 124 kDa
- ID gène
- 23394
- NCBI Accession
- NM_015339, NP_056154
- UniProt
- Q9H2P0
- Pathways
- Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process
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