LNX1 anticorps (C-Term)

N° du produit ABIN2781236

Cet anticorps Lapin Polyclonal détecte spécifiquement LNX1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin et Cobaye.

Aperçu rapide pour LNX1 anticorps (C-Term) (ABIN2781236)

Antigène: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LNX1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LNX1 anticorps

Épitope: C-Term

Séquence: SHREWDLPIY VISVEPGGVI SRDGRIKTGD ILLNVDGVEL TEVSRSEAVA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LNX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human LNX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 632 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LNX1

Antigène: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Autre désignation: LNX1

Sujet: LNX1 is a membrane-bound protein that is involved in signal transduction and protein interactions. LNX1 is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis.This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.
Alias Symbols: LNX, MPDZ, PDZRN2
Protein Interaction Partner: GRB2, TRIP13, ZCCHC10, ROPN1, NECAB2, PRR13, ZNF581, APIP, MEMO1, ZNF593, OSGIN1, NME7, OSBP2, DNPEP, ISCU, MTUS2, RUVBL2, NEK6, RFPL3, AIDA, GDI1, ROBO3, PBLD, LSM2, HOMEZ, TRIM54, AGTRAP, LGALS14, TRIM39, NXT2, ZFP64, POMGNT1, GOLPH3L, TRMT12, FAM118A,
Protein Size: 632

Poids moléculaire: 70 kDa

ID gène: 84708

NCBI Accession: NM_032622, NP_116011