HECTD2 anticorps (C-Term)

N° du produit ABIN2781287

Cet anticorps Lapin Polyclonal détecte spécifiquement HECTD2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Rat, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).Il a été cité dans 1 publication.

Aperçu rapide pour HECTD2 anticorps (C-Term) (ABIN2781287)

Antigène: HECTD2 (HECT Domain Containing 2 (HECTD2))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Rat, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HECTD2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HECTD2 anticorps

Épitope: C-Term

Fonction: HECTD2 Antibody - C-terminal region

Séquence: TDLTIKYFWD VVLGFPLDLQ KKLLHFTTGS DRVPVGGMAD LNFKISKNET

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HECTD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HECTD2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43481-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HECTD2 (ABIN2781287)

Sun, Wang, He, Sweeney, Liu, Brown, Balk, Lee, Kantoff: "MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A." dans: Oncogene, Vol. 33, Issue 21, pp. 2790-800, (2014) (PubMed).

Détails sur HECTD2

Antigène: HECTD2 (HECT Domain Containing 2 (HECTD2))

Autre désignation: HECTD2

Sujet:

Background Information: HECTD2 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Gene Name: HECT domain containing E3 ubiquitin protein ligase 2

Alternative Symbols: FLJ16050

Protein Name: Probable E3 ubiquitin-protein ligase HECTD2

Poids moléculaire: 88kDa

ID gène: 143279

NCBI Accession: NP_877497

UniProt: Q5RD78