M6PR anticorps (N-Term)

N° du produit ABIN2781302

Cet anticorps Lapin Polyclonal détecte spécifiquement M6PR dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin et Cheval.

Aperçu rapide pour M6PR anticorps (N-Term) (ABIN2781302)

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp M6PR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-M6PR anticorps

Épitope: N-Term

Séquence: RLKPLFNKSF ESTVGQGSDT YIYIFRVCRE AGNHTSGAGL VQINKSNGKE

Homologie: Cow: 85%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against M6PR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human M6PR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 277 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur M6PR

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Autre désignation: M6PR

Sujet: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
Alias Symbols: CD-MPR, FLJ32994, MPR46, SMPR, MPR 46, MPR-46
Protein Interaction Partner: FBXO6, ATP4A, SNRPGP15, HPDL, RPS28, RPL37A, RPL6, RANBP2, NDUFS4, NDUFB4, ACP2, ACOX1, GGA3, GGA1, JUN, UBC, GGA2, PLIN3, REN,
Protein Size: 277

Poids moléculaire: 28 kDa

ID gène: 4074

NCBI Accession: NM_002355, NP_002346

UniProt: P20645