PAM anticorps (C-Term)

N° du produit ABIN2781312

Cet anticorps anti-PAM est un anticorps Lapin Polyclonal détectant PAM dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour PAM anticorps (C-Term) (ABIN2781312)

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PAM anticorps

Épitope: C-Term

Séquence: GLNLGNFFAS RKGYSRKGFD RLSTEGSDQE KEDDGSESEE EYSAPLPALA

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 93%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against PAM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human PAM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAM

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Autre désignation: PAM

Sujet: This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Alias Symbols: PAL, PHM
Protein Size: 335

Poids moléculaire: 36 kDa

ID gène: 5066

NCBI Accession: NM_000919, NP_000910

UniProt: P19021