PAM anticorps (C-Term)

N° du produit ABIN2781312

Détail du produit anti-PAM anticorps

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAM est non-conjugé

Application: Western Blotting (WB)

Séquence: GLNLGNFFAS RKGYSRKGFD RLSTEGSDQE KEDDGSESEE EYSAPLPALA

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 93%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against PAM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human PAM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAM

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Autre désignation: PAM (PAM Produits)

Synonymes: anticorps PAL, anticorps PHM, anticorps pal, anticorps phm, anticorps pamb, anticorps CG3832, anticorps Dmel\\CG3832, anticorps dPHM, anticorps AE-I, anticorps PAL-A, anticorps PHM-A, anticorps pama, anticorps si:dkeyp-35f12.2, anticorps peptidylglycine alpha-amidating monooxygenase, anticorps peptidylglycine alpha-amidating monooxygenase S homeolog, anticorps Peptidylglycine-alpha-hydroxylating monooxygenase, anticorps peptidylglycine alpha-amidating monooxygenase L homeolog, anticorps PAM, anticorps Pam, anticorps pam.S, anticorps CHLREDRAFT_150435, anticorps sce7070, anticorps pam, anticorps Phm, anticorps pam.L

Sujet: This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Alias Symbols: PAL, PHM
Protein Size: 335

Poids moléculaire: 36 kDa

ID gène: 5066

NCBI Accession: NM_000919, NP_000910

UniProt: P19021