HDAC4 anticorps (C-Term)

N° du produit ABIN2781487

L’anticorps Lapin Polyclonal anti-HDAC4 a été validé pour WB et ChIP. Il convient pour détecter HDAC4 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval et Saccharomyces cerevisiae.

Aperçu rapide pour HDAC4 anticorps (C-Term) (ABIN2781487)

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC4 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-HDAC4 anticorps

Épitope: C-Term

Séquence: SSTVGHSLIE AQKCEKEEAE TVTAMASLSV GVKPAEKRSE EEPMEEEPPL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 77%, Human: 100%, Mouse: 86%, Rat: 93%, Yeast: 82%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Hdac4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1076 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HDAC4

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Autre désignation: Hdac4

Sujet: Hdac4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Alias Symbols: 4932408F19Rik, AI047285
Protein Interaction Partner: Rfxank, Mef2d, Mef2c, Mef2a, Dnajb6, Tnf, Runx2, Myocd, Ppp2ca, Gli2, Creb1, Atm, Ywhab, Ifrd1,
Protein Size: 1076

Poids moléculaire: 118 kDa

ID gène: 208727

NCBI Accession: NM_207225, NP_997108

UniProt: Q6NZM9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process