HDAC4 anticorps (C-Term)
Aperçu rapide pour HDAC4 anticorps (C-Term) (ABIN2781487)
Antigène
Voir toutes HDAC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Hdac4 Antibody - C-terminal region
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Séquence
- SSTVGHSLIE AQKCEKEEAE TVTAMASLSV GVKPAEKRSE EEPMEEEPPL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 77%, Human: 100%, Mouse: 86%, Rat: 93%, Yeast: 82%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against Hdac4. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac4
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43602-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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Autre désignation
- Hdac4
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Sujet
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Background Information: Hdac4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Alternative Symbols: HD4, 4932408F19Rik
Protein Name: Histone deacetylase 4
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Poids moléculaire
- 118kDa
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ID gène
- 208727
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NCBI Accession
- NP_997108
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UniProt
- Q6NZM9
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Antigène
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