Thyroperoxidase anticorps (N-Term)

N° du produit ABIN2781812

Cet anticorps anti-Thyroperoxidase Polyclonal Lapin (ABIN2781812) détecte spécifiquement Thyroperoxidase dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Porc, Lapin et Saccharomyces cerevisiae.

Aperçu rapide pour Thyroperoxidase anticorps (N-Term) (ABIN2781812)

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Porc, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thyroperoxidase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Thyroperoxidase anticorps

Épitope: N-Term

Séquence: GASNTALARW LPPVYEDGFS QPRGWNPGFL YNGFPLPPVR EVTRHVIQVS

Homologie: Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Yeast: 83%

Attributs du produit: This is a rabbit polyclonal antibody against TPO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TPO

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Thyroperoxidase

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Autre désignation: Thyroid Peroxidase

Sujet: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Protein Interaction Partner: DUOX1, TXNDC11,
Protein Size: 611

Poids moléculaire: 67 kDa

ID gène: 7173

Pathways: Thyroid Hormone Synthesis