M-CSF/CSF1 anticorps (N-Term)

N° du produit ABIN2781822

Cet anticorps anti-M-CSF/CSF1 est un anticorps Lapin Polyclonal détectant M-CSF/CSF1 dans WB et IHC. Adapté pour Humain, Rat, Chien, Cobaye et Lapin.

Aperçu rapide pour M-CSF/CSF1 anticorps (N-Term) (ABIN2781822)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivité: Humain, Rat, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp M-CSF/CSF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-M-CSF/CSF1 anticorps

Épitope: N-Term

Séquence: PPTTWLGSLL LLVCLLASRS ITEEVSEYCS HMIGSGHLQS LQRLIDSQME

Homologie: Dog: 85%, Guinea Pig: 85%, Human: 100%, Rabbit: 92%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CSF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CSF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 438 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur M-CSF/CSF1

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: CSF1

Sujet: CSF1 is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. CSF1 may be involved in development of the placenta. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Four transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: MCSF, MGC31930, CSF-1
Protein Interaction Partner: NOTCH2NL, SGTA, FHL3, GAB3, SOCS1, TNF, CSF1R, HLA-B, CSF1, SLA2, UBC, CBL, PIK3R2, SMARCA4,
Protein Size: 438

Poids moléculaire: 45 kDa

ID gène: 1435

NCBI Accession: NM_172210, NP_757349

UniProt: Q5VVF3

Pathways: Signalisation RTK