POR anticorps (N-Term)

N° du produit ABIN2781830

Détail du produit anti-POR anticorps

Antigène: POR (P450 (Cytochrome) Oxidoreductase (POR))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IDNALVVFCM ATYGEGDPTD NAQDFYDWLQ ETDVDLSGVK FAVFGLGNKT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against POR. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human POR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 680 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POR

Antigène: POR (P450 (Cytochrome) Oxidoreductase (POR))

Autre désignation: POR (POR Produits)

Synonymes: anticorps CPR, anticorps CYPOR, anticorps P450R, anticorps POR, anticorps CCR, anticorps CG11567, anticorps DMR, anticorps DmCPR, anticorps Dmel\\CG11567, anticorps NCPR, anticorps P450, anticorps cpr, anticorps zgc:110032, anticorps npr, anticorps xpor, anticorps 4933424M13Rik, anticorps PORCINO, anticorps T5J17.90, anticorps T5J17_90, anticorps TFC C, anticorps TUBULIN-FOLDING COFACTOR C, anticorps cytochrome p450 oxidoreductase, anticorps P450 (cytochrome) oxidoreductase, anticorps ADP-ribosylation factor interacting protein 2, anticorps Cytochrome P450 reductase, anticorps P450 (cytochrome) oxidoreductase a, anticorps P450 (cytochrome) oxidoreductase L homeolog, anticorps NADPH--cytochrome P450 reductase, anticorps C-CAP/cofactor C-like domain-containing protein, anticorps POR, anticorps Arfip2, anticorps Por, anticorps Cpr, anticorps pora, anticorps por.L, anticorps LOC100406157, anticorps por, anticorps LOC100619047

Sujet: POR is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this POR gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R
Protein Interaction Partner: UBC, CYP2C9, PGRMC1, STAT1, INSIG1, CYP3A4, CYP2E1, CYP2D6, CYP2C19, CYP2A6, CYP1A2, UBD, SUMO2, RABEPK, FANCC, CYB5A, CYP17A1, XRCC6, HMOX1,
Protein Size: 680

Poids moléculaire: 77 kDa

ID gène: 5447

NCBI Accession: NM_000941, NP_000932

UniProt: Q63HL4

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome