GALC anticorps (Middle Region)

N° du produit ABIN2782035

L’anticorps anti-GALC Polyclonal Lapin est utilisé pour la détection de GALC dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye et Porc. Il a été validé pour WB.

Aperçu rapide pour GALC anticorps (Middle Region) (ABIN2782035)

Antigène: GALC (Galactosylceramidase (GALC))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GALC anticorps

Épitope: Middle Region

Fonction: GALC Antibody - middle region

Séquence: LMTAQEPWSG HYVVESPVWV SAHTTQFTQP GWYYLKTVGH LEKGGSYVAL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GALC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GALC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44847-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GALC

Antigène: GALC (Galactosylceramidase (GALC))

Autre désignation: GALC

Sujet:

Background Information: GALC is a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy.This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: Galactosylceramidase

Alternative Symbols: -

Protein Name: Galactocerebrosidase

Poids moléculaire: 73kDa

ID gène: 2581

NCBI Accession: NP_000144

UniProt: P54803