SPPL2B anticorps (N-Term)
Aperçu rapide pour SPPL2B anticorps (N-Term) (ABIN2782089)
Antigène
Voir toutes SPPL2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- AHLPHDLSKA SFLQLRNWTA SLLCSAADLP ARGFSNQIPL VARGNCTFYE
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Homologie
- Cow: 79%, Horse: 86%, Human: 100%, Pig: 79%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against SPPL2B. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPPL2B
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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Autre désignation
- SPPL2B
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Sujet
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SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
Alias Symbols: IMP-4, IMP4, PSH4, PSL1
Protein Size: 307 -
Poids moléculaire
- 33 kDa
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ID gène
- 56928
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NCBI Accession
- NM_152988, NP_694533
Antigène
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