SPPL2B anticorps (N-Term)

N° du produit ABIN2782089

Cet anticorps anti-SPPL2B Polyclonal Lapin (ABIN2782089) détecte spécifiquement SPPL2B dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Boeuf (Vache), Cheval et Porc.

Aperçu rapide pour SPPL2B anticorps (N-Term) (ABIN2782089)

Antigène: SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

Reactivité: Humain, Rat, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPPL2B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPPL2B anticorps

Épitope: N-Term

Séquence: AHLPHDLSKA SFLQLRNWTA SLLCSAADLP ARGFSNQIPL VARGNCTFYE

Homologie: Cow: 79%, Horse: 86%, Human: 100%, Pig: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SPPL2B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPPL2B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPPL2B

Antigène: SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

Autre désignation: SPPL2B

Sujet: SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
Alias Symbols: IMP-4, IMP4, PSH4, PSL1
Protein Size: 307

Poids moléculaire: 33 kDa

ID gène: 56928

NCBI Accession: NM_152988, NP_694533