anticorps SPPL2B, anticorps wu:fc16e01, anticorps wu:fc85d12, anticorps zgc:136525, anticorps MGC147524, anticorps IMP-4, anticorps IMP4, anticorps PSH4, anticorps PSL1, anticorps 3110056O03Rik, anticorps AW550292, anticorps RGD1308556, anticorps signal peptide peptidase-like 2, anticorps signal peptide peptidase like 2B, anticorps signal peptide peptidase like 2B S homeolog, anticorps signal peptide peptidase-like 2B, anticorps sppl2, anticorps sppl2b, anticorps sppl2b.S, anticorps SPPL2B, anticorps Sppl2b
Sujet
SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Alias Symbols: IMP-4, IMP4, PSH4, PSL1 Protein Size: 307