ADCY8 anticorps (Middle Region)

N° du produit ABIN2782113

L’anticorps anti-ADCY8 Polyclonal Lapin est utilisé pour la détection de ADCY8 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin et Cheval. Il a été validé pour WB.

Aperçu rapide pour ADCY8 anticorps (Middle Region) (ABIN2782113)

Antigène: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADCY8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADCY8 anticorps

Épitope: Middle Region

Fonction: ADCY8 Antibody - middle region

Séquence: EIYVKGISEQ EGKIKTYFLL GRVQPNPFIL PPRRLPGQYS LAAVVLGLVQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ADCY8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ADCY8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45047-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ADCY8

Antigène: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Autre désignation: ADCY8

Sujet:

Background Information: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Adenylate cyclase 8 (brain)

Alternative Symbols: AC8, ADCY3, HBAC1

Protein Name: Adenylate cyclase type 8

Poids moléculaire: 140kDa

ID gène: 114

NCBI Accession: NP_001106

UniProt: P40145

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma