HMOX1 anticorps (N-Term)

N° du produit ABIN2782158

Cet anticorps Lapin Polyclonal détecte spécifiquement HMOX1 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Porc, Chien, Boeuf (Vache), Cobaye, Lapin et Chévre et a été mentionné dans 2+ publications.

Aperçu rapide pour HMOX1 anticorps (N-Term) (ABIN2782158)

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reactivité: Humain, Rat, Souris, Porc, Chien, Boeuf (Vache), Cobaye, Lapin, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMOX1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HMOX1 anticorps

Épitope: N-Term

Séquence: ERPQPDSMPQ DLSEALKEAT KEVHTQAENA EFMRNFQKGQ VTRDGFKLVM

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HMOX1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HMOX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 288 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HMOX1 (ABIN2782158)

Kawahara, Gasperini, Myers, Widrick, Eran, Serafini, Alexander, Pletcher, Morris, Kunkel: "Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling." dans: Human molecular genetics, Vol. 23, Issue 7, pp. 1869-78, (2014) (PubMed).

Hausmann, Paul, Kellermeier, Frey, Schölmerich, Falk, Menzel, Fried, Herfarth, Rogler: "(GT)N dinucleotide repeat polymorphism of haem oxygenase-1 promotor region is not associated with inflammatory bowel disease risk or disease course." dans: Clinical and experimental immunology, Vol. 153, Issue 1, pp. 81-5, (2008) (PubMed).

Détails sur HMOX1

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Autre désignation: HMOX1

Sujet: HMOX1 belongs to the heme oxygenase family. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2.
Alias Symbols: HO-1, HSP32, bK286B10
Protein Interaction Partner: CCDC155, UBC, TUT1, CPSF1, ASL, POT1, TERF1, ELAVL1, HMX1, BLVRB, AKT1, NOS1, HMOX1, POR, UFD1L, PSMD2,
Protein Size: 288

Poids moléculaire: 33 kDa

ID gène: 3162

NCBI Accession: NM_002133, NP_002124

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome