JAG2 anticorps (N-Term)

N° du produit ABIN2782165

Cet anticorps Lapin Polyclonal détecte spécifiquement JAG2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Porc.Il a été cité dans 1 publication.

Aperçu rapide pour JAG2 anticorps (N-Term) (ABIN2782165)

Antigène: JAG2 (Jagged 2 (JAG2))

Reactivité: Humain, Souris, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-JAG2 anticorps

Épitope: N-Term

Fonction: JAG2 Antibody - N-terminal region

Séquence: RAQGRGRLPR RLLLLLALWV QAARPMGYFE LQLSALRNVN GELLSGACCD

Homologie: Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against JAG2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human JAG2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45254-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-JAG2 (ABIN2782165)

Passos Gregorio, Gattaz, Tavares, Kieling, Timm, Wang, Berg Rasmussen, Werge, Dias-Neto: "Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects." dans: Schizophrenia research, Vol. 88, Issue 1-3, pp. 275-82, (2006) (PubMed).

Détails sur JAG2

Antigène: JAG2 (Jagged 2 (JAG2))

Autre désignation: JAG2

Sujet:

Background Information: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch protein family are transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Jagged 2

Alternative Symbols: HJ2, SER2

Protein Name: Protein jagged-2

Poids moléculaire: 130kDa

ID gène: 3714

NCBI Accession: NP_002217

UniProt: Q9Y219

Pathways: Signalisation Notch, Sensory Perception of Sound