LTB anticorps (N-Term)

N° du produit ABIN2782173

Cet anticorps Lapin Polyclonal détecte spécifiquement LTB dans WB. Il présente une réactivité envers Humain, Cheval, Lapin et Cobaye.

Aperçu rapide pour LTB anticorps (N-Term) (ABIN2782173)

Antigène: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Reactivité: Humain, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LTB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LTB anticorps

Épitope: N-Term

Séquence: AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS

Homologie: Guinea Pig: 79%, Horse: 91%, Human: 100%, Rabbit: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LTB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 244 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LTB

Antigène: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Autre désignation: LTB

Sujet: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244

Poids moléculaire: 25 kDa

ID gène: 4050

NCBI Accession: NM_002341, NP_002332

UniProt: Q06643

Pathways: Signalisation NF-kappaB