LTB anticorps (N-Term)
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- Antigène Voir toutes LTB Anticorps
- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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Épitope
- N-Term
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Reactivité
- Humain, Cheval, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LTB est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
- Homologie
- Guinea Pig: 79%, Horse: 91%, Human: 100%, Rabbit: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human LTB
- Top Product
- Discover our top product LTB Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 244 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
- Autre désignation
- LTB (LTB Produits)
- Synonymes
- anticorps AI662801, anticorps LTbeta, anticorps Tnfc, anticorps Tnfsf3, anticorps p33, anticorps TNFC, anticorps TNFSF3, anticorps LT-b, anticorps LT-beta, anticorps TNF-C, anticorps lymphotoxin B, anticorps lymphotoxin beta, anticorps Ltb, anticorps LTB
- Sujet
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Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244 - Poids moléculaire
- 25 kDa
- ID gène
- 4050
- NCBI Accession
- NM_002341, NP_002332
- UniProt
- Q06643
- Pathways
- Signalisation NF-kappaB
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